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Liliya Markova Pekova

University Hospital Stara Zagora, Bulgaria

Title: Ulceroglandular tularemia: Clinical course and outcome in 5 cases

Biography

Biography: Liliya Markova Pekova

Abstract

Introduction: Tularemia is an acute febrile zoonosis, which is potential life threatening disease. The most popular clinical form is ulceroglandular. Aim: Materials & Methods: In a period of 8 months (December 2014-July 2015) through the Clinic of Infectious diseases of University Hospital Stara Zagora, Bulgaria, 5 patients with ulceroglandular form of Tularemia were passed; they were 4 men and 1 woman, aged from 52 to 73 years. Clinical, epidemiological, laboratorial and serological investigations were provided. Results & Discussion: Three of patients were hunters, fired wild rabbits and the rest two took part in breaking up and cooking the game. After an incubation period mean 4.8±1.4 days in all was appeared a primary affect in region of the fingers. Three had redness in eyes, on face and oropharynx. Later on the toxic syndrome a regional painful lymphadenitis was appeared. Two patients had dyspeptic syndrome with vomiting and diarrhea, no appetite. All had enlarged liver, two had scanty maculopapular rash. The diagnosis was proved by degree agglutination type Vidal at the Referent Laboratory of Particularly Dangerous Infection, National Center of Infectious, Parasite Diseases, Sofia. The antibacterial treatment was a combination of 4-quinolones and aminoglycosides. The outcome was favorable in all patients. Conclusion: Because tularemia is not so common disease, it could be easy left out. It must be suspected when there were unusual temperature, redness in eyes and glandular syndrome with corresponding epidemiological situation.