Biography
Nito Panganiban, Ph.D., is Professor and Interim Division Chair of Microbiology at the Tulane National Primate Research Center, Chief Scientific Officer at Peptineo, and a member of the Department of Microbiology and Immunology at the Tulane University School of Medicine. Dr. Panganiban received his PhD in Microbiology and Immunology from the University of Washington, where he carried out research on bacteriophage RNA processing in Helen Whiteley's lab. He did two years of postdoctoral work on retrovirus replication in Howard Temin's lab at the McArdle Lab for Cancer Research at the University of Wisconsin before joining the faculty at McArdle. He was then a Professor in the Department of Molecular Genetics and Microbiology at the University of New Mexico Health Sciences Center. He moved to Tulane in 2012. Past work has centered on retrovirus replication including HIV. Dr. Panganiban does research on diverse emerging RNA viruses, with emphasis on pathogenic, zoonotic RNA viruses including members of the bunya- and flavivirus families including Zika virus, Rift Valley Fever, Crimean Congo hemorrhagic fever, and hantaviruses. He is an expert in multiple facets of molecular virology and nonhuman primate models for RNA viruses, vaccines, virus-host interaction, high containment facilities, molecular biology, and genomics. In addition to his academic research and teaching, he is CSO of Peptineo (a biotech firm based in Albuquerque), and has served on numerous NIH, and additional, national committees and panels, and has served as a consultant for biotech and multi-investigator consortia.
Research Interest
Differential gene expression using transcriptome analysis, RNA biology, RNA viruses, emerging viruses, zoonotic viruses, host-pathogen interaction, viruses requiring high containment facilities, genomics
Biography
Dr. Montelaro is a Professor in the Department of Microbiology and Molecular Genetics of the University of Pittsburgh School of Medicine with secondary appointments in the Department of Infectious Diseases and Immunology (Graduate School or Public Health) and the Department of Medicine Division of Infectious Diseases. He serves as the Co-Director of the Center for Vaccine Research and the Scientific Director of the Peptide Synthesis Core. He received his PhD in Biochemistry in 1975 from the University of Wisconsin-Madison. His research interest is in viral immunology and vaccine development, especially as related to AIDS, emerging diseases, and biodefense.
Research Interest
The primary focus of the Montelaro lab is to elucidate the intricate interactions between viral pathogens and host immune responses to determine the mechanisms by with host immunity contributes to protection and disease and to serve as a basis for the development of effective vaccines. A particular interest of the lab is to develop effective strategies to overcome the challenge of natural viral antigenic variation that has evolved as a common complication to the development of effective vaccines to important viral diseases, including those related to biodefense and emerging infectious diseases. Systems currently under investigation include HIV-1 and related animal lentiviruses (SHIV, SIV, and EIAV). Studies in these systems include investigation of the nature and role of antigenic variation during infection, the development of novel assays to characterize virus-specific innate, humoral, and cellular immune responses, and the design of engineered immunogens for effective vaccination against variant strains of a particular virus. In addition to these vaccine related studies, the lab also maintains a research program to develop novel de novo antimicrobial peptides (engineered cationic amphipathic peptides, or eCAPs) that can be used to inactivate a diverse spectrum of bacteria or enveloped viruses in a prophylactic or therapeutic treatment modalities.
Biography
C. A. Guzman graduated in Medicine and become Board Certified in Medical Bacteriology in Argentina. Later, he graduated as Doctor of Medicine and Surgery and obtained his Doctorate in Microbiological Sciences (University Genoa, Italy). In 1994 he became Head of the Vaccine Group (German Research Centre for Biotechnology, Germany). In 2005 he was appointed Head of the Department of Vaccinology and Applied Microbiology (HZI), becoming later also APL-Professor at the Medical School and Member of the Centre for Individualized Infection Medicine (Hannover). His work was instrumental for developing new adjuvants and antigen delivery systems, leading to more than 200 publications.
Research Interest