Monoclonal antibodies

Monoclonal antibodies are antibodies that are made by identical immune cells. These can have monovalent affinity, in that they bind to the same epitope. In divergence, polyclonal antibodies bind to multiple epitopes and made by several different plasma cell lineages. These antibodies are secreted by different B cell lineages and are used for autoimmune diseases. Antigen prompts the B-lymphocytes to produce IgG Immunoglobulin’s.

About 24 million people in the United States are affected by an autoimmune disease.

 

  • Hypoxanthine-guanine-phosphoribosyl transferase (HGPRT)
  • Autoimmune diseases
  • Apoptosis
  • Hybridoma technology